🍽️ Bile Acid Sequestrant

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  1. Lowering Cholesterol Levels: Bile acid sequestrants are effective in reducing low-density lipoprotein cholesterol (LDL-C) levels, also known as "bad" cholesterol, which is a major risk factor for cardiovascular disease. By binding to bile acids in the intestine, bile acid sequestrants prevent their reabsorption, leading to increased bile acid excretion in the feces and decreased bile acid pool size. As a compensatory mechanism, the liver utilizes circulating cholesterol to synthesize new bile acids, thereby reducing LDL-C levels in the blood.

  2. Cardiovascular Disease Risk Reduction: Lowering LDL-C levels with bile acid sequestrants has been shown to reduce the risk of cardiovascular events such as heart attack, stroke, and coronary artery disease. By lowering cholesterol levels, bile acid sequestrants help slow the progression of atherosclerosis (hardening and narrowing of arteries) and decrease the likelihood of plaque formation and rupture, which can lead to cardiovascular events.

  3. Treatment of Hyperlipidemia: Bile acid sequestrants are indicated for the treatment of hyperlipidemia, including heterozygous familial hypercholesterolemia and primary hyperlipidemia, particularly in patients who cannot tolerate or do not respond adequately to statin therapy. Bile acid sequestrants may be used as monotherapy or in combination with other cholesterol-lowering medications, such as statins, ezetimibe, or fibrates, to achieve target LDL-C levels and reduce cardiovascular risk.

  4. Gastrointestinal Side Effects: Bile acid sequestrants may cause gastrointestinal side effects such as constipation, bloating, flatulence, abdominal discomfort, and dyspepsia due to their physical binding action in the intestine. These side effects are dose-dependent and may vary among individual patients. Patients should be advised to increase dietary fiber intake, maintain adequate hydration, and engage in regular physical activity to help alleviate gastrointestinal symptoms associated with bile acid sequestrant therapy.

  5. Drug Interactions: Bile acid sequestrants may interact with other medications, including oral medications, by interfering with their absorption in the gastrointestinal tract. To minimize the risk of drug interactions, bile acid sequestrants should be administered at least 1 hour before or 4 hours after other medications, including vitamins, minerals, and fat-soluble medications such as warfarin, digoxin, thyroid hormones, and certain antiepileptic drugs.

  6. Nutrient Absorption: Bile acid sequestrants may impair the absorption of fat-soluble vitamins (A, D, E, K) and other nutrients from the intestine due to their binding action on bile acids. Patients receiving long-term bile acid sequestrant therapy should be monitored for nutritional deficiencies and may require supplementation with fat-soluble vitamins or other nutrients as needed.

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Data Contradictions β€” Limits of Certainity

Impacted of Bile Acid Sequestrant On Probiotics

Rank Probiotic Impact
species Clostridium beijerinckii Increases
species Clostridium butyricum Increases

Bacteria Impacted by Bile Acid Sequestrant

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Atopobiaceae family Increases 👪 Source Study
Bacteroidaceae family Increases 👪 Source Study
Bacteroidaceae family Increases 👪 Source Study
Clostridiaceae family Increases 👪 Source Study
Coprobacillaceae family Increases 👪 Source Study
Eubacteriaceae family Increases 👪 Source Study
Lachnospiraceae family Increases 👪 Source Study
Oscillospiraceae family Increases 👪 Source Study
Prevotellaceae family Increases 👪 Source Study
Rikenellaceae family Increases 👪 Source Study
Lachnospiraceae family Increases 📓 Source Study
Clostridioides genus Decreases 👪 Source Study
Roseburia genus Decreases 👪 Source Study
Olsenella genus Increases ⚗️ Source Study
Acetatifactor genus Increases 👶 Source Study
Acetitomaculum genus Increases 👶 Source Study
Agathobacter genus Increases 👶 Source Study
Anaerobium genus Increases 👶 Source Study
Anaerobutyricum genus Increases 👶 Source Study
Anaerocolumna genus Increases 👶 Source Study
Anaeromicropila genus Increases 👶 Source Study
Anaeropeptidivorans genus Increases 👶 Source Study
Anaerosacchariphilus genus Increases 👶 Source Study
Anaerosporobacter genus Increases 👶 Source Study
Anaerostipes genus Increases 👶 Source Study
Anaerotaenia genus Increases 👶 Source Study
Anaerotignum genus Increases 👶 Source Study
Bariatricus genus Increases 👶 Source Study
Blautia genus Increases 👶 Source Study
Butyribacter genus Increases 👶 Source Study
Butyrivibrio genus Increases 👶 Source Study
Candidatus Epulonipiscium genus Increases 👶 Source Study
Catenibacillus genus Increases 👶 Source Study
Catonella genus Increases 👶 Source Study
Chordicoccus genus Increases 👶 Source Study
Coprococcus genus Increases 👶 Source Study
Cuneatibacter genus Increases 👶 Source Study
Dorea genus Increases 👶 Source Study
Eisenbergiella genus Increases 👶 Source Study
Enterocloster genus Increases 👶 Source Study
Extibacter genus Increases 👶 Source Study
Faecalicatena genus Increases 👶 Source Study
Faecalimonas genus Increases 👶 Source Study
Frisingicoccus genus Increases 👶 Source Study
Fusicatenibacter genus Increases 👶 Source Study
Herbinix genus Increases 👶 Source Study
Hespellia genus Increases 👶 Source Study
Johnsonella genus Increases 👶 Source Study
Kineothrix genus Increases 👶 Source Study
Lachnoanaerobaculum genus Increases 👶 Source Study
Lachnobacterium genus Increases 👶 Source Study
Lachnoclostridium genus Increases 👶 Source Study
Lachnospira genus Increases 👶 Source Study
Lachnotalea genus Increases 👶 Source Study
Lacrimispora genus Increases 👶 Source Study
Lientehia genus Increases 👶 Source Study
Marvinbryantia genus Increases 👶 Source Study
Mediterraneibacter genus Increases 👶 Source Study
Merdimonas genus Increases 👶 Source Study
Mobilitalea genus Increases 👶 Source Study
Moryella genus Increases 👶 Source Study
Muricomes genus Increases 👶 Source Study
Murimonas genus Increases 👶 Source Study
Niameybacter genus Increases 👶 Source Study
Novisyntrophococcus genus Increases 👶 Source Study
Oliverpabstia genus Increases 👶 Source Study
Oribacterium genus Increases 👶 Source Study
Parasporobacterium genus Increases 👶 Source Study
Porcincola genus Increases 👶 Source Study
Pseudobutyrivibrio genus Increases 👶 Source Study
Qiania genus Increases 👶 Source Study
Robinsoniella genus Increases 👶 Source Study
Roseburia genus Increases 👶 Source Study
Schaedlerella genus Increases 👶 Source Study
Sellimonas genus Increases 👶 Source Study
Shuttleworthia genus Increases 👶 Source Study
Simiaoa genus Increases 👶 Source Study
Sporobacterium genus Increases 👶 Source Study
Sporofaciens genus Increases 👶 Source Study
Stomatobaculum genus Increases 👶 Source Study
Syntrophococcus genus Increases 👶 Source Study
Tyzzerella genus Increases 👶 Source Study
Waltera genus Increases 👶 Source Study
Wansuia genus Increases 👶 Source Study
Wujia genus Increases 👶 Source Study
Klebsiella genus Increases 👪 Source Study Pathogen
Segatella genus Increases 👪 Source Study
Alistipes genus Increases 📓 Source Study
Bacteroides genus Increases 📓 Source Study
Bacteroides genus Increases 📓 Source Study
Blautia genus Increases 📓 Source Study
Clostridium genus Increases 📓 Source Study Pathogen
Coprobacillus genus Increases 📓 Source Study
Eubacterium genus Increases 📓 Source Study
Olsenella genus Increases 📓 Source Study
Oscillospira genus Increases 📓 Source Study
Prevotella genus Increases 📓 Source Study
unclassified Olsenella no rank Increases ⚗️ Source Study
environmental samples no rank Increases 👶 Source Study
environmental samples no rank Increases 👶 Source Study
environmental samples no rank Increases 👶 Source Study
environmental samples no rank Increases 👶 Source Study
environmental samples no rank Increases 👶 Source Study
environmental samples no rank Increases 👶 Source Study
environmental samples no rank Increases 👶 Source Study
environmental samples no rank Increases 👶 Source Study
environmental samples no rank Increases 👶 Source Study
Lachnospiraceae incertae sedis no rank Increases 👶 Source Study
unclassified Alistipes no rank Increases 👶 Source Study
unclassified Bacteroides no rank Increases 👶 Source Study
unclassified Bacteroides no rank Increases 👶 Source Study
unclassified Blautia no rank Increases 👶 Source Study
unclassified Clostridium no rank Increases 👶 Source Study
unclassified Coprobacillus no rank Increases 👶 Source Study
unclassified Eubacterium (in: firmicutes) no rank Increases 👶 Source Study
unclassified Lachnospiraceae no rank Increases 👶 Source Study
unclassified Olsenella no rank Increases 👶 Source Study
unclassified Oscillospira no rank Increases 👶 Source Study
unclassified Prevotella no rank Increases 👶 Source Study
Eubacteriales order Increases 👪 Source Study
Clostridioides difficile species Decreases 📓 Source Study Colitis
Roseburia intestinalis species Decreases 📓 Source Study
Olsenella sp. 1183 species Increases ⚗️ Source Study
[Butyribacterium] methylotrophicum species Increases 👶 Source Study
[Eubacterium] cellulosolvens species Increases 👶 Source Study
Alistipes communis species Increases 👶 Source Study
Alistipes dispar species Increases 👶 Source Study
Alistipes finegoldii species Increases 👶 Source Study
Alistipes ihumii species Increases 👶 Source Study
Alistipes indistinctus species Increases 👶 Source Study
Alistipes inops species Increases 👶 Source Study
Alistipes massiliensis species Increases 👶 Source Study
Alistipes megaguti species Increases 👶 Source Study
Alistipes obesi species Increases 👶 Source Study
Alistipes onderdonkii species Increases 👶 Source Study
Alistipes provencensis species Increases 👶 Source Study
Alistipes putredinis species Increases 👶 Source Study
Alistipes senegalensis species Increases 👶 Source Study
Alistipes shahii species Increases 👶 Source Study
Alistipes timonensis species Increases 👶 Source Study
Bacteroides acidifaciens species Increases 👶 Source Study
Bacteroides acidifaciens species Increases 👶 Source Study
Bacteroides caccae species Increases 👶 Source Study
Bacteroides caccae species Increases 👶 Source Study
Bacteroides caecigallinarum species Increases 👶 Source Study
Bacteroides caecigallinarum species Increases 👶 Source Study
Bacteroides caecimuri species Increases 👶 Source Study
Bacteroides caecimuri species Increases 👶 Source Study
Bacteroides caecimuris species Increases 👶 Source Study
Bacteroides caecimuris species Increases 👶 Source Study
Bacteroides cellulosilyticus species Increases 👶 Source Study
Bacteroides cellulosilyticus species Increases 👶 Source Study
Bacteroides chinchillae species Increases 👶 Source Study
Bacteroides chinchillae species Increases 👶 Source Study
Bacteroides clarus species Increases 👶 Source Study
Bacteroides clarus species Increases 👶 Source Study
Bacteroides coprosuis species Increases 👶 Source Study
Bacteroides coprosuis species Increases 👶 Source Study
Bacteroides cutis species Increases 👶 Source Study
Bacteroides cutis species Increases 👶 Source Study
Bacteroides denticanum species Increases 👶 Source Study
Bacteroides denticanum species Increases 👶 Source Study
Bacteroides eggerthii species Increases 👶 Source Study
Bacteroides eggerthii species Increases 👶 Source Study
Bacteroides faecalis species Increases 👶 Source Study
Bacteroides faecalis species Increases 👶 Source Study
Bacteroides faecichinchillae species Increases 👶 Source Study
Bacteroides faecichinchillae species Increases 👶 Source Study
Bacteroides faecis species Increases 👶 Source Study
Bacteroides faecis species Increases 👶 Source Study
Bacteroides faecium species Increases 👶 Source Study
Bacteroides faecium species Increases 👶 Source Study
Bacteroides finegoldii species Increases 👶 Source Study
Bacteroides finegoldii species Increases 👶 Source Study
Bacteroides fluxus species Increases 👶 Source Study
Bacteroides fluxus species Increases 👶 Source Study
Bacteroides fragilis species Increases 👶 Source Study H02076 Bacteroides infection
Bacteroides fragilis species Increases 👶 Source Study H02076 Bacteroides infection
Bacteroides galacturonicus species Increases 👶 Source Study
Bacteroides galacturonicus species Increases 👶 Source Study
Bacteroides gallinaceum species Increases 👶 Source Study
Bacteroides gallinaceum species Increases 👶 Source Study
Bacteroides gallinarum species Increases 👶 Source Study
Bacteroides gallinarum species Increases 👶 Source Study
Bacteroides graminisolvens species Increases 👶 Source Study
Bacteroides graminisolvens species Increases 👶 Source Study
Bacteroides helcogenes species Increases 👶 Source Study
Bacteroides helcogenes species Increases 👶 Source Study
Bacteroides heparinolyticus species Increases 👶 Source Study
Bacteroides heparinolyticus species Increases 👶 Source Study
Bacteroides humanifaecis species Increases 👶 Source Study
Bacteroides humanifaecis species Increases 👶 Source Study
Bacteroides ihuae species Increases 👶 Source Study
Bacteroides ihuae species Increases 👶 Source Study
Bacteroides intestinalis species Increases 👶 Source Study
Bacteroides intestinalis species Increases 👶 Source Study
Bacteroides koreensis species Increases 👶 Source Study
Bacteroides koreensis species Increases 👶 Source Study
Bacteroides kribbi species Increases 👶 Source Study
Bacteroides kribbi species Increases 👶 Source Study
Bacteroides luhongzhouii species Increases 👶 Source Study
Bacteroides luhongzhouii species Increases 👶 Source Study
Bacteroides luti species Increases 👶 Source Study
Bacteroides luti species Increases 👶 Source Study
Bacteroides mediterraneensis species Increases 👶 Source Study
Bacteroides mediterraneensis species Increases 👶 Source Study
Bacteroides ndongoniae species Increases 👶 Source Study
Bacteroides ndongoniae species Increases 👶 Source Study
Bacteroides nordii species Increases 👶 Source Study
Bacteroides nordii species Increases 👶 Source Study
Bacteroides oleiciplenus species Increases 👶 Source Study
Bacteroides oleiciplenus species Increases 👶 Source Study
Bacteroides ovatus species Increases 👶 Source Study
Bacteroides ovatus species Increases 👶 Source Study
Bacteroides propionicifaciens species Increases 👶 Source Study
Bacteroides propionicifaciens species Increases 👶 Source Study
Bacteroides pyogenes species Increases 👶 Source Study
Bacteroides pyogenes species Increases 👶 Source Study
Bacteroides reticulotermitis species Increases 👶 Source Study
Bacteroides reticulotermitis species Increases 👶 Source Study
Bacteroides rodentium species Increases 👶 Source Study
Bacteroides rodentium species Increases 👶 Source Study
Bacteroides salyersiae species Increases 👶 Source Study
Bacteroides salyersiae species Increases 👶 Source Study
Bacteroides sp species Increases 👶 Source Study
Bacteroides sp species Increases 👶 Source Study
Bacteroides sp. C13EG172 species Increases 👶 Source Study
Bacteroides sp. C13EG172 species Increases 👶 Source Study
Bacteroides stercorirosoris species Increases 👶 Source Study
Bacteroides stercorirosoris species Increases 👶 Source Study
Bacteroides stercoris species Increases 👶 Source Study
Bacteroides stercoris species Increases 👶 Source Study
Bacteroides thetaiotaomicron species Increases 👶 Source Study
Bacteroides thetaiotaomicron species Increases 👶 Source Study
Bacteroides timonensis species Increases 👶 Source Study
Bacteroides timonensis species Increases 👶 Source Study
Bacteroides uniformis species Increases 👶 Source Study Infectious bacteria
Bacteroides uniformis species Increases 👶 Source Study Infectious bacteria
Bacteroides xylanisolvens species Increases 👶 Source Study
Bacteroides xylanisolvens species Increases 👶 Source Study
Bacteroides zhangwenhongii species Increases 👶 Source Study
Bacteroides zhangwenhongii species Increases 👶 Source Study
Bacteroides zoogleoformans species Increases 👶 Source Study
Bacteroides zoogleoformans species Increases 👶 Source Study
Blautia argi species Increases 👶 Source Study
Blautia caecimuris species Increases 👶 Source Study
Blautia coccoides species Increases 👶 Source Study
Blautia difficilis species Increases 👶 Source Study
Blautia faecicola species Increases 👶 Source Study
Blautia faecis species Increases 👶 Source Study
Blautia glucerasea species Increases 👶 Source Study
Blautia hansenii species Increases 👶 Source Study
Blautia hominis species Increases 👶 Source Study
Blautia hydrogenotrophica species Increases 👶 Source Study
Blautia intestinalis species Increases 👶 Source Study
Blautia liquoris species Increases 👶 Source Study
Blautia luti species Increases 👶 Source Study
Blautia marasmi species Increases 👶 Source Study
Blautia massiliensis (ex Durand et al. 2017) species Increases 👶 Source Study
Blautia obeum species Increases 👶 Source Study
Blautia producta species Increases 👶 Source Study
Blautia pseudococcoides species Increases 👶 Source Study
Blautia schinkii species Increases 👶 Source Study
Blautia stercoris species Increases 👶 Source Study
Blautia tarda species Increases 👶 Source Study
Blautia wexlerae species Increases 👶 Source Study
Clostridium aceticum species Increases 👶 Source Study
Clostridium acetireducens species Increases 👶 Source Study
Clostridium acetobutylicum species Increases 👶 Source Study
Clostridium acidisoli species Increases 👶 Source Study
Clostridium aestuarii species Increases 👶 Source Study
Clostridium akagii species Increases 👶 Source Study
Clostridium algidicarnis species Increases 👶 Source Study
Clostridium algifaecis species Increases 👶 Source Study
Clostridium aminobutyricum species Increases 👶 Source Study
Clostridium amylolyticum species Increases 👶 Source Study
Clostridium argentinense species Increases 👶 Source Study
Clostridium aurantibutyricum species Increases 👶 Source Study
Clostridium autoethanogenum species Increases 👶 Source Study
Clostridium baratii species Increases 👶 Source Study
Clostridium beijerinckii species Increases 👶 Source Study
Clostridium boliviensis species Increases 👶 Source Study
Clostridium bornimense species Increases 👶 Source Study
Clostridium botulinum species Increases 👶 Source Study Botulinum poisoning
Clostridium bovifaecis species Increases 👶 Source Study
Clostridium bovipellis species Increases 👶 Source Study
Clostridium bowmanii species Increases 👶 Source Study
Clostridium butyricum species Increases 👶 Source Study
Clostridium cadaveris species Increases 👶 Source Study
Clostridium caliptrosporum species Increases 👶 Source Study
Clostridium carboxidivorans species Increases 👶 Source Study
Clostridium carnis species Increases 👶 Source Study
Clostridium cavendishii species Increases 👶 Source Study
Clostridium celatum species Increases 👶 Source Study
Clostridium cellulovorans species Increases 👶 Source Study
Clostridium chartatabidum species Increases 👶 Source Study
Clostridium chauvoei species Increases 👶 Source Study
Clostridium chromiireducens species Increases 👶 Source Study
Clostridium cochlearium species Increases 👶 Source Study
Clostridium colicanis species Increases 👶 Source Study
Clostridium collagenovorans species Increases 👶 Source Study
Clostridium cuniculi species Increases 👶 Source Study
Clostridium cylindrosporum species Increases 👶 Source Study
Clostridium diolis species Increases 👶 Source Study
Clostridium disporicum species Increases 👶 Source Study
Clostridium drakei species Increases 👶 Source Study
Clostridium estertheticum species Increases 👶 Source Study
Clostridium fallax species Increases 👶 Source Study
Clostridium felsineum species Increases 👶 Source Study
Clostridium fermenticellae species Increases 👶 Source Study
Clostridium fessum species Increases 👶 Source Study
Clostridium formicaceticum species Increases 👶 Source Study
Clostridium frigidicarnis species Increases 👶 Source Study
Clostridium frigoris species Increases 👶 Source Study
Clostridium fungisolvens species Increases 👶 Source Study
Clostridium fusiformis species Increases 👶 Source Study
Clostridium ganghwense species Increases 👶 Source Study
Clostridium gasigenes species Increases 👶 Source Study
Clostridium gelidum species Increases 👶 Source Study
Clostridium grantii species Increases 👶 Source Study
Clostridium haemolyticum species Increases 👶 Source Study
Clostridium homopropionicum species Increases 👶 Source Study
Clostridium hveragerdense species Increases 👶 Source Study
Clostridium hydrogeniformans species Increases 👶 Source Study
Clostridium intestinale species Increases 👶 Source Study
Clostridium isatidis species Increases 👶 Source Study
Clostridium jeddahense species Increases 👶 Source Study
Clostridium jeddahitimonense species Increases 👶 Source Study
Clostridium kluyveri species Increases 👶 Source Study
Clostridium kogasense species Increases 👶 Source Study
Clostridium lacusfryxellense species Increases 👶 Source Study
Clostridium liquoris species Increases 👶 Source Study
Clostridium ljungdahlii species Increases 👶 Source Study
Clostridium longisporum species Increases 👶 Source Study
Clostridium lundense species Increases 👶 Source Study
Clostridium magnum species Increases 👶 Source Study
Clostridium malenominatum species Increases 👶 Source Study
Clostridium manihotivorum species Increases 👶 Source Study
Clostridium massiliamazoniense species Increases 👶 Source Study
Clostridium merdae species Increases 👶 Source Study
Clostridium minihomine species Increases 👶 Source Study
Clostridium moniliforme species Increases 👶 Source Study
Clostridium neonatale species Increases 👶 Source Study
Clostridium nigeriense species Increases 👶 Source Study
Clostridium nitrophenolicum species Increases 👶 Source Study
Clostridium novyi species Increases 👶 Source Study
Clostridium oceanicum species Increases 👶 Source Study
Clostridium oryzae species Increases 👶 Source Study
Clostridium paraputrificum species Increases 👶 Source Study
Clostridium paridis species Increases 👶 Source Study
Clostridium pasteurianum species Increases 👶 Source Study
Clostridium perfringens species Increases 👶 Source Study Food poisoning, gas gangrene
Clostridium phoceensis species Increases 👶 Source Study
Clostridium polyendosporum species Increases 👶 Source Study
Clostridium porci species Increases 👶 Source Study
Clostridium proteolyticus species Increases 👶 Source Study
Clostridium putrefaciens species Increases 👶 Source Study
Clostridium quinii species Increases 👶 Source Study
Clostridium rhizosphaerae species Increases 👶 Source Study
Clostridium saccharobutylicum species Increases 👶 Source Study
Clostridium saccharoperbutylacetonicum species Increases 👶 Source Study
Clostridium sardiniense species Increases 👶 Source Study
Clostridium sartagoforme species Increases 👶 Source Study
Clostridium saudiense species Increases 👶 Source Study
Clostridium scatologenes species Increases 👶 Source Study
Clostridium schirmacherense species Increases 👶 Source Study
Clostridium segne species Increases 👶 Source Study
Clostridium senegalense species Increases 👶 Source Study
Clostridium septicum species Increases 👶 Source Study
Clostridium sp. TF01-11 species Increases 👶 Source Study
Clostridium sporogenes species Increases 👶 Source Study
Clostridium subterminale species Increases 👶 Source Study
Clostridium sulfidigenes species Increases 👶 Source Study
Clostridium swellfunianum species Increases 👶 Source Study
Clostridium taeniosporum species Increases 👶 Source Study
Clostridium tagluense species Increases 👶 Source Study
Clostridium tarantellae species Increases 👶 Source Study
Clostridium tepidiprofundi species Increases 👶 Source Study
Clostridium tertium species Increases 👶 Source Study
Clostridium tetani species Increases 👶 Source Study Tetanus
Clostridium tetanomorphum species Increases 👶 Source Study
Clostridium thermarum species Increases 👶 Source Study
Clostridium thermoamylolyticum species Increases 👶 Source Study
Clostridium thermobutyricum species Increases 👶 Source Study
Clostridium thermopalmarium species Increases 👶 Source Study
Clostridium thiosulfatireducens species Increases 👶 Source Study
Clostridium tunisiense species Increases 👶 Source Study
Clostridium tyrobutyricum species Increases 👶 Source Study
Clostridium uliginosum species Increases 👶 Source Study
Clostridium vincentii species Increases 👶 Source Study
Clostridium vulturis species Increases 👶 Source Study
Coprobacillus cateniformis species Increases 👶 Source Study
Coprobacillus sp. D6 species Increases 👶 Source Study
Eubacterium barkeri species Increases 👶 Source Study
Eubacterium callanderi species Increases 👶 Source Study
Eubacterium coprostanoligenes species Increases 👶 Source Study
Eubacterium limosum species Increases 👶 Source Study
Eubacterium maltosivorans species Increases 👶 Source Study
Eubacterium multiforme species Increases 👶 Source Study
Eubacterium oxidoreducens species Increases 👶 Source Study
Eubacterium plexicaudatum species Increases 👶 Source Study
Eubacterium pyruvativorans species Increases 👶 Source Study
Eubacterium ramulus species Increases 👶 Source Study
Eubacterium rangiferina species Increases 👶 Source Study
Eubacterium ruminantium species Increases 👶 Source Study
Eubacterium segne species Increases 👶 Source Study
Eubacterium uniforme species Increases 👶 Source Study
Eubacterium ventriosum species Increases 👶 Source Study
Eubacterium xylanophilum species Increases 👶 Source Study
Olsenella profusa species Increases 👶 Source Study
Olsenella timonensis species Increases 👶 Source Study
Olsenella uli species Increases 👶 Source Study
Olsenella urininfantis species Increases 👶 Source Study
Oscillospira guilliermondii species Increases 👶 Source Study
Prevotella amnii species Increases 👶 Source Study
Prevotella aurantiaca species Increases 👶 Source Study
Prevotella bivia species Increases 👶 Source Study Infectious bacteria
Prevotella brevis species Increases 👶 Source Study
Prevotella conceptionensis species Increases 👶 Source Study
Prevotella corporis species Increases 👶 Source Study
Prevotella dentalis species Increases 👶 Source Study
Prevotella dentasini species Increases 👶 Source Study
Prevotella denticola species Increases 👶 Source Study
Prevotella disiens species Increases 👶 Source Study
Prevotella falsenii species Increases 👶 Source Study
Prevotella fusca species Increases 👶 Source Study
Prevotella herbatica species Increases 👶 Source Study
Prevotella histicola species Increases 👶 Source Study
Prevotella intermedia species Increases 👶 Source Study Infectious bacteria
Prevotella jejuni species Increases 👶 Source Study
Prevotella marseillensis species Increases 👶 Source Study
Prevotella melaninogenica species Increases 👶 Source Study Pathogen
Prevotella merdae species Increases 👶 Source Study
Prevotella micans species Increases 👶 Source Study
Prevotella multiformis species Increases 👶 Source Study
Prevotella nigrescens species Increases 👶 Source Study
Prevotella oryzae species Increases 👶 Source Study
Prevotella pallens species Increases 👶 Source Study
Prevotella pectinovora species Increases 👶 Source Study
Prevotella phocaeensis species Increases 👶 Source Study
Prevotella rara species Increases 👶 Source Study
Prevotella ruminicola species Increases 👶 Source Study
Prevotella scopos species Increases 👶 Source Study
Prevotella sp. P5-119 species Increases 👶 Source Study
Prevotella veroralis species Increases 👶 Source Study
Klebsiella pneumoniae species Increases 📓 Source Study H00301 Klebsiella infection, Pneumonia
Segatella copri species Increases 📓 Source Study Over 70%ile Indicator of mycotoxin present
Clostridioides difficile 002-P50-2011 strain Decreases 👶 Source Study
Clostridioides difficile 2007855 strain Decreases 👶 Source Study
Clostridioides difficile 342 strain Decreases 👶 Source Study
Clostridioides difficile 6041 strain Decreases 👶 Source Study
Clostridioides difficile 630 strain Decreases 👶 Source Study H00338 Pseudomembranous colitis
Clostridioides difficile ATCC 43255 strain Decreases 👶 Source Study
Clostridioides difficile ATCC 9689 = DSM 1296 strain Decreases 👶 Source Study
Clostridioides difficile BI9 strain Decreases 👶 Source Study
Clostridioides difficile BJ08 strain Decreases 👶 Source Study
Clostridioides difficile CD196 strain Decreases 👶 Source Study H00338 Pseudomembranous colitis
Clostridioides difficile CD40 strain Decreases 👶 Source Study
Clostridioides difficile DA00195 strain Decreases 👶 Source Study
Clostridioides difficile E85 strain Decreases 👶 Source Study
Clostridioides difficile F321 strain Decreases 👶 Source Study
Clostridioides difficile F501 strain Decreases 👶 Source Study
Clostridioides difficile genomovar ribotype_087 strain Decreases 👶 Source Study
Clostridioides difficile M120 strain Decreases 👶 Source Study
Clostridioides difficile NAP08 strain Decreases 👶 Source Study
Clostridioides difficile P28 strain Decreases 👶 Source Study
Clostridioides difficile P29 strain Decreases 👶 Source Study
Clostridioides difficile P38 strain Decreases 👶 Source Study
Clostridioides difficile P51 strain Decreases 👶 Source Study
Clostridioides difficile QCD-23m63 strain Decreases 👶 Source Study
Clostridioides difficile QCD-37x79 strain Decreases 👶 Source Study
Clostridioides difficile QCD-63q42 strain Decreases 👶 Source Study
Clostridioides difficile QCD-76w55 strain Decreases 👶 Source Study
Roseburia intestinalis L1-82 strain Decreases 👶 Source Study
Roseburia intestinalis M50/1 strain Decreases 👶 Source Study
Roseburia intestinalis XB6B4 strain Decreases 👶 Source Study
Clostridium sp. ASF502 strain Increases 👶 Source Study
Klebsiella pneumoniae JM45 strain Increases 👶 Source Study
Klebsiella pneumoniae KCTC 2242 strain Increases 👶 Source Study
Klebsiella pneumoniae KP-1 strain Increases 👶 Source Study
Segatella copri DSM 18205 strain Increases 👶 Source Study
Klebsiella pneumoniae subsp. pneumoniae subspecies Increases 👶 Source Study H00301 Klebsiella infection
Klebsiella pneumoniae subsp. rhinoscleromatis subspecies Increases 👶 Source Study

Impact of Bile Acid Sequestrant on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.6 -0.6
Acne 1.3 0.3 3.33
ADHD 1.5 2.4 -0.6
Age-Related Macular Degeneration and Glaucoma 1 0.4 1.5
Allergic Rhinitis (Hay Fever) 0.4 1.8 -3.5
Allergies 3.6 1.6 1.25
Allergy to milk products 0.3 3 -9
Alopecia (Hair Loss) 1.4 -1.4
Alzheimer's disease 4.7 3.7 0.27
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1 1.9 -0.9
Ankylosing spondylitis 2.8 3.9 -0.39
Anorexia Nervosa 3 0.9 2.33
Antiphospholipid syndrome (APS) 0.5 0.5 0
Asthma 1 2 -1
Atherosclerosis 1.4 1.1 0.27
Atrial fibrillation 3 3.5 -0.17
Autism 7.2 7.1 0.01
benign prostatic hyperplasia 0.5 0.5
Bipolar Disorder 0.8 2.1 -1.63
Brain Trauma 2.1 0.3 6
Breast Cancer 0.2 -0.2
Carcinoma 2.6 4.1 -0.58
Celiac Disease 3.2 1.2 1.67
Cerebral Palsy 1.8 1.2 0.5
Chronic Fatigue Syndrome 2.6 3.9 -0.5
Chronic Kidney Disease 1 1.2 -0.2
Chronic Lyme 0.6 0 0
Chronic Obstructive Pulmonary Disease (COPD) 1.5 1.3 0.15
Chronic Urticaria (Hives) 1.6 0.6 1.67
Coagulation / Micro clot triggering bacteria 2 0.6 2.33
Colorectal Cancer 0.7 4.4 -5.29
Constipation 1.3 2.3 -0.77
Coronary artery disease 2.3 1.2 0.92
COVID-19 9.6 6.5 0.48
Crohn's Disease 6.2 6.3 -0.02
cystic fibrosis 0.9 0 0
deep vein thrombosis 1.4 0.6 1.33
Depression 6.8 8.1 -0.19
Dermatomyositis 0.4 -0.4
Eczema 1.7 0.6 1.83
Endometriosis 0.5 2.8 -4.6
Eosinophilic Esophagitis 0.3 0.3
Epilepsy 2 3.7 -0.85
erectile dysfunction 0.3 0.6 -1
Fibromyalgia 3.3 2.9 0.14
Functional constipation / chronic idiopathic constipation 4.2 5.8 -0.38
gallstone disease (gsd) 1.2 2 -0.67
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1 1.2 -0.2
Generalized anxiety disorder 1.4 0.6 1.33
giant cell arteritis 0.6 0.3 1
Glioblastoma 1.5 0.6 1.5
Gout 0.6 0.3 1
Graves' disease 1.8 1.7 0.06
Halitosis 0.4 2.1 -4.25
Hashimoto's thyroiditis 1.7 3.3 -0.94
Hemorrhoidal disease, Hemorrhoids, Piles 0.6 -0.6
Hidradenitis Suppurativa 0.2 0.6 -2
Histamine Issues,Mast Cell Issue, DAO Insufficiency 1 2.2 -1.2
hypercholesterolemia (High Cholesterol) 1.5 -1.5
hyperglycemia 1 0.4 1.5
Hyperlipidemia (High Blood Fats) 0.6 0.6
hypersomnia 0.4 0.3 0.33
hypertension (High Blood Pressure 5 1.8 1.78
Hypothyroidism 1.9 0.5 2.8
Hypoxia 0.6 0.6 0
IgA nephropathy (IgAN) 4.2 0.8 4.25
Inflammatory Bowel Disease 6.5 2.4 1.71
Insomnia 2 1.7 0.18
Intelligence 1.5 2.5 -0.67
Intracranial aneurysms 0.6 1.6 -1.67
Irritable Bowel Syndrome 3.8 5 -0.32
Liver Cirrhosis 3.4 5.4 -0.59
Long COVID 8 5.5 0.45
Low bone mineral density 2.1 0.6 2.5
Lung Cancer 1.8 0.2 8
ME/CFS with IBS 0.8 1.2 -0.5
ME/CFS without IBS 0.8 1.5 -0.88
Menopause 0.2 0.2 0
Metabolic Syndrome 6.4 8 -0.25
Mood Disorders 7 9 -0.29
multiple chemical sensitivity [MCS] 0.4 0.4
Multiple Sclerosis 4.3 2.7 0.59
Multiple system atrophy (MSA) 0.4 0.2 1
myasthenia gravis 0.3 0.2 0.5
Neuropathy (all types) 1.1 -1.1
neuropsychiatric disorders (PANDAS, PANS) 0.4 0.6 -0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 4.5 2.4 0.88
Obesity 6.5 6 0.08
obsessive-compulsive disorder 5.4 4.1 0.32
Osteoarthritis 1.8 -1.8
Osteoporosis 2.1 1.5 0.4
pancreatic cancer 0.3 -0.3
Parkinson's Disease 4.7 4.6 0.02
Polycystic ovary syndrome 1.5 3.3 -1.2
Postural orthostatic tachycardia syndrome 0.2 0.8 -3
Premenstrual dysphoric disorder 0.2 0.6 -2
primary biliary cholangitis 0.5 0.6 -0.2
Psoriasis 3.4 1.8 0.89
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 5.7 6.3 -0.11
Rosacea 0.6 0 0
Schizophrenia 2.3 5 -1.17
scoliosis 0.6 1.1 -0.83
sensorineural hearing loss 0.4 0.3 0.33
Sjögren syndrome 3.3 2.4 0.38
Sleep Apnea 2.5 0.9 1.78
Small Intestinal Bacterial Overgrowth (SIBO) 1.8 -1.8
Stress / posttraumatic stress disorder 2.1 2.2 -0.05
Systemic Lupus Erythematosus 2.7 4 -0.48
Tic Disorder 1.7 1.5 0.13
Tourette syndrome 0.9 0.9
Type 1 Diabetes 2 3.2 -0.6
Type 2 Diabetes 5.3 7.1 -0.34
Ulcerative colitis 5.2 3.7 0.41
Unhealthy Ageing 2.1 1.9 0.11

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