🍽️ flunixin meglumine,(prescription)

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  1. Anti-inflammatory Effects: Flunixin meglumine works by inhibiting the production of prostaglandins, which are inflammatory mediators involved in the body's response to injury or inflammation. By reducing prostaglandin levels, flunixin meglumine helps alleviate inflammation and associated symptoms.

  2. Analgesic (Pain-Relieving) Effects: Flunixin meglumine has analgesic properties, meaning it helps relieve pain. It is often used to manage pain associated with various conditions, including musculoskeletal injuries, postoperative pain, colic in horses, and other painful inflammatory conditions in animals.

  3. Fever Reduction: Flunixin meglumine can help reduce fever by inhibiting the production of prostaglandins, which play a role in regulating body temperature. It is commonly used to treat fever associated with infections or inflammatory conditions in animals.

  4. Colic in Horses: Colic is a common and potentially life-threatening condition in horses characterized by abdominal pain. Flunixin meglumine is frequently used in horses to relieve pain and reduce inflammation associated with colic episodes.

  5. Musculoskeletal Injuries: Flunixin meglumine is used to manage pain and inflammation associated with musculoskeletal injuries, such as strains, sprains, and arthritis, in various animal species.

  6. Postoperative Pain Management: After surgical procedures, animals may experience pain and inflammation at the surgical site. Flunixin meglumine can be administered postoperatively to help alleviate pain and discomfort.

  7. Dosage and Administration: The dosage and route of administration of flunixin meglumine vary depending on the species, the severity of the condition being treated, and the veterinarian's recommendation. It is typically administered by injection, either intravenously or intramuscularly.

  8. Duration of Treatment: Flunixin meglumine is usually prescribed for short-term use to manage acute pain, inflammation, or fever in animals. The duration of treatment depends on the specific condition and the animal's response to therapy.

  9. Side Effects: While generally safe when used as directed, flunixin meglumine can cause side effects in some animals, including gastrointestinal ulceration, renal toxicity, and reduced blood flow to the kidneys. Long-term or excessive use of flunixin meglumine may increase the risk of adverse effects.

  10. Contraindications: Flunixin meglumine should not be used in animals with a known hypersensitivity to NSAIDs or a history of gastrointestinal ulceration. It should be used with caution in animals with preexisting renal or hepatic impairment.

  11. Drug Interactions: Flunixin meglumine may interact with other medications, including other NSAIDs, corticosteroids, and drugs that affect renal function. Veterinarians should be aware of potential drug interactions and adjust treatment accordingly.

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Data Contradictions β€” Limits of Certainity

Impacted of flunixin meglumine,(prescription) On Probiotics

Rank Probiotic Impact
species Akkermansia muciniphila Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium longum Reduces
species Escherichia coli Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by flunixin meglumine,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Odoribacter genus Decreases 👪 Source Study
Clostridioides genus Decreases 👪 Source Study
Bacteroides genus Decreases 👪 Source Study
Parabacteroides genus Decreases 👪 Source Study BMI, fat percent,blood pressure
Collinsella genus Decreases 👪 Source Study proinflammatory
Veillonella genus Decreases 👪 Source Study
Bifidobacterium genus Decreases 👪 Source Study
Ruminococcus genus Decreases 👪 Source Study
Phocaeicola genus Decreases 👪 Source Study
Blautia genus Decreases 👪 Source Study
Coprococcus genus Decreases 👪 Source Study
Dorea genus Decreases 👪 Source Study
Thomasclavelia genus Decreases 👪 Source Study
Agathobacter genus Decreases 👪 Source Study
Escherichia genus Decreases 👪 Source Study
Roseburia genus Decreases 👪 Source Study
Akkermansia genus Decreases 👪 Source Study
Streptococcus genus Decreases 👪 Source Study
Clostridium genus Decreases 👪 Source Study Pathogen
Lachnospira genus Decreases 👪 Source Study
unclassified Robinsoniella no rank Decreases ⚗️ Source Study
unclassified Fusobacterium no rank Decreases ⚗️ Source Study
unclassified Negativicoccus no rank Decreases ⚗️ Source Study
Escherichia coli O80:H26 no rank Decreases 👶 Source Study
Eggerthellales order Decreases ⚗️ Source Study
Escherichia coli O145 serogroup Decreases 👶 Source Study
Escherichia coli O157 serogroup Decreases 👶 Source Study
Escherichia coli O26 serogroup Decreases 👶 Source Study
Escherichia coli O43 serogroup Decreases 👶 Source Study
Escherichia coli O1:H42 serotype Decreases 👶 Source Study
Escherichia coli O104:H4 serotype Decreases 👶 Source Study
Escherichia coli O121:H19 serotype Decreases 👶 Source Study
Escherichia coli O127:H6 serotype Decreases 👶 Source Study
Escherichia coli O139:H28 serotype Decreases 👶 Source Study
Escherichia coli O157:H7 serotype Decreases 👶 Source Study bloody diarrhea
Escherichia coli O44:H18 serotype Decreases 👶 Source Study
Escherichia coli O55:H7 serotype Decreases 👶 Source Study
Escherichia coli O6:H16 serotype Decreases 👶 Source Study
Escherichia coli O7:K1 serotype Decreases 👶 Source Study
Odoribacter splanchnicus species Decreases 📓 Source Study
Bacteroides ovatus species Decreases 📓 Source Study
Bacteroides xylanisolvens species Decreases 📓 Source Study
Clostridioides difficile species Decreases 📓 Source Study Colitis
Bacteroides caccae species Decreases 📓 Source Study
Parabacteroides merdae species Decreases 📓 Source Study Infectious bacteria
Bacteroides thetaiotaomicron species Decreases 📓 Source Study
Collinsella aerofaciens species Decreases 📓 Source Study
Parabacteroides distasonis species Decreases 📓 Source Study
Bacteroides uniformis species Decreases 📓 Source Study Infectious bacteria
Bacteroides fragilis species Decreases 📓 Source Study H02076 Bacteroides infection
Veillonella parvula species Decreases 📓 Source Study
Bifidobacterium adolescentis species Decreases 📓 Source Study
Ruminococcus bromii species Decreases 📓 Source Study
Bifidobacterium longum species Decreases 📓 Source Study
Phocaeicola vulgatus species Decreases 📓 Source Study
Blautia obeum species Decreases 📓 Source Study
Coprococcus comes species Decreases 📓 Source Study
Dorea formicigenerans species Decreases 📓 Source Study
Roseburia hominis species Decreases 📓 Source Study
Thomasclavelia ramosa species Decreases 📓 Source Study
Anaerofustis stercorihominis species Decreases ⚗️ Source Study
Asaccharospora irregularis species Decreases ⚗️ Source Study
Negativicoccus sp. S5-A15 species Decreases ⚗️ Source Study
Agathobacter rectalis species Decreases 📓 Source Study
Escherichia coli species Decreases 📓 Source Study Diarrheal disease in children and travelers, Foodborne diarrhea outbreaks, hemorrhagic colitis, hemolytic-uremic syndrome
Paraprevotella clara species Decreases ⚗️ Source Study
Slackia sp. NATTS species Decreases ⚗️ Source Study
Akkermansia muciniphila species Decreases 📓 Source Study
Pseudoflavonifractor capillosus species Decreases ⚗️ Source Study
[Collinsella] massiliensis species Decreases ⚗️ Source Study
Parvibacter caecicola species Decreases ⚗️ Source Study
Streptococcus parasanguinis species Decreases 📓 Source Study
Clostridium perfringens species Decreases 📓 Source Study Food poisoning, gas gangrene
Lachnospira eligens species Decreases 📓 Source Study
Roseburia intestinalis species Decreases 📓 Source Study
Coriobacterineae suborder Decreases ⚗️ Source Study
Bifidobacterium longum subsp. infantis subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. longum subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. suillum subspecies Decreases 👶 Source Study
Chlamydiae/Verrucomicrobia group superphylum Decreases ⚗️ Source Study

Impact of flunixin meglumine,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Acne 0.3 -0.3
ADHD 4.7 0.2 22.5
Age-Related Macular Degeneration and Glaucoma 0.3 0.5 -0.67
Allergic Rhinitis (Hay Fever) 1 1.5 -0.5
Allergies 4.3 1.4 2.07
Allergy to milk products 1 0.8 0.25
Alopecia (Hair Loss) 1.8 1.8
Alzheimer's disease 2.4 3.3 -0.38
Amyotrophic lateral sclerosis (ALS) Motor Neuron 2.4 0.6 3
Ankylosing spondylitis 2.7 0.8 2.38
Anorexia Nervosa 0.5 1.2 -1.4
Antiphospholipid syndrome (APS) 1.1 1.1
Asthma 0.3 0.7 -1.33
Atherosclerosis 1 1.2 -0.2
Atrial fibrillation 2.7 1.3 1.08
Autism 5.3 5.7 -0.08
Barrett esophagus cancer 0.3 0.1 2
benign prostatic hyperplasia 0.1 0.1
Bipolar Disorder 1.3 0.9 0.44
Brain Trauma 0.7 0.5 0.4
Carcinoma 3.1 2.9 0.07
Celiac Disease 2 3.5 -0.75
Cerebral Palsy 0.8 1.1 -0.38
Chronic Fatigue Syndrome 3.5 6.4 -0.83
Chronic Kidney Disease 1 0.9 0.11
Chronic Lyme 0.5 -0.5
Chronic Obstructive Pulmonary Disease (COPD) 0.5 0.3 0.67
Chronic Urticaria (Hives) 0.7 0.9 -0.29
Coagulation / Micro clot triggering bacteria 0.8 0.7 0.14
Colorectal Cancer 3.1 0.8 2.88
Constipation 1.1 0.3 2.67
Coronary artery disease 0.8 0.8 0
COVID-19 10.1 10.5 -0.04
Crohn's Disease 5.6 4.3 0.3
cystic fibrosis 0.2 0.8 -3
deep vein thrombosis 0.2 0.4 -1
Depression 7.4 6.3 0.17
Dermatomyositis 0.1 0.3 -2
Eczema 0.4 1.2 -2
Endometriosis 2.2 1.1 1
Eosinophilic Esophagitis 0.3 -0.3
Epilepsy 2.4 2.6 -0.08
Fibromyalgia 2.2 2.1 0.05
Functional constipation / chronic idiopathic constipation 4.7 2.8 0.68
gallstone disease (gsd) 1.7 0.4 3.25
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.6 0.6 1.67
Generalized anxiety disorder 0.5 1.6 -2.2
giant cell arteritis 0 0
Glioblastoma 0.1 -0.1
Gout 0.2 -0.2
Graves' disease 1.7 1 0.7
Halitosis 0.8 0.1 7
Hashimoto's thyroiditis 1.4 0.8 0.75
Hidradenitis Suppurativa 0.1 0.3 -2
Histamine Issues,Mast Cell Issue, DAO Insufficiency 2.2 0.3 6.33
hypercholesterolemia (High Cholesterol) 0.5 0.1 4
hyperglycemia 0.1 1.7 -16
Hyperlipidemia (High Blood Fats) 0.8 0.4 1
hypersomnia 0.3 -0.3
hypertension (High Blood Pressure 2.2 3.9 -0.77
Hypothyroidism 0.8 -0.8
Hypoxia 1 1
IgA nephropathy (IgAN) 3.2 -3.2
Inflammatory Bowel Disease 2.5 5.9 -1.36
Insomnia 0.8 0.6 0.33
Intelligence 1.2 1.2
Intracranial aneurysms 1.5 0.4 2.75
Irritable Bowel Syndrome 3.7 4.2 -0.14
Liver Cirrhosis 3.4 2.1 0.62
Long COVID 6.2 7.5 -0.21
Low bone mineral density 0.3 -0.3
Lung Cancer 1 0.9 0.11
ME/CFS with IBS 0.1 2.2 -21
ME/CFS without IBS 0.2 2.3 -10.5
Menopause 2.2 2.2
Metabolic Syndrome 6.3 6.9 -0.1
Mood Disorders 9.3 6.3 0.48
multiple chemical sensitivity [MCS] 0.4 0.3 0.33
Multiple Sclerosis 2.5 3.4 -0.36
Multiple system atrophy (MSA) 0.6 0.8 -0.33
Neuropathy (all types) 0.4 0.1 3
neuropsychiatric disorders (PANDAS, PANS) 0.7 0.7
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 1.1 4.1 -2.73
NonCeliac Gluten Sensitivity 0.3 -0.3
Obesity 6.5 3.4 0.91
obsessive-compulsive disorder 6.8 2.2 2.09
Osteoarthritis 0.9 0.3 2
Osteoporosis 1.2 0.9 0.33
pancreatic cancer 0.6 0.6
Parkinson's Disease 1.9 2.2 -0.16
Polycystic ovary syndrome 2.1 1.6 0.31
Postural orthostatic tachycardia syndrome 0 0.5 0
Premenstrual dysphoric disorder 1 0.5 1
primary biliary cholangitis 0.2 1.3 -5.5
Psoriasis 3.6 2.2 0.64
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 3.9 3.4 0.15
Rosacea 0.6 0.1 5
Schizophrenia 5.7 1.2 3.75
scoliosis 0.2 0.3 -0.5
Sjögren syndrome 2.3 3.3 -0.43
Sleep Apnea 1.1 1 0.1
Small Intestinal Bacterial Overgrowth (SIBO) 0.2 0.6 -2
Stress / posttraumatic stress disorder 1.8 1.6 0.13
Systemic Lupus Erythematosus 3.1 1.4 1.21
Tic Disorder 1.3 1 0.3
Tourette syndrome 0.1 0.5 -4
Type 1 Diabetes 4 1.4 1.86
Type 2 Diabetes 6.8 6.1 0.11
Ulcerative colitis 1.6 4.7 -1.94
Unhealthy Ageing 3.4 1.3 1.62

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